$270,000 Drug. One Competitor. Billion-Dollar Market.

Phase 3 trial targets recurrent pericarditis with an oral therapy that could disrupt the only approved treatment. And their heart failure program launches in 2026.

Asian shares advance after a retreat on Wall Street

ELAINE KURTENBACH
December 01, 2025

BANGKOK (AP) -- Asian shares mostly advanced on Tuesday after U.S. stocks gave back some of last week's rally, pressured by rising global bond yields.

U.S. futures and oil prices were little changed.

Tokyo's Nikkei 225 gained 0.5% to 49,534.36, with financial shares the biggest gainers after the governor of the central bank hinted at a possible hike to interest rates this month.

In Hong Kong, the Hang Seng jumped 0.7% to 26,209.07, while the Shanghai Composite index slipped 0.3% to 3,902.78.

Australia's S&P/ASX 200 added 0.2% to 8,582.80.

The Kospi in South Korea jumped 1.5% to 3,977.85, led by buying of technology shares like Samsung Electronics, which surged 2.8%. Chip maker SK Hynix leaped 3.4%.

Taiwan's benchmark Taiex climbed 1%, while the Sensex in India edged 0.1% lower.

On Monday, the S&P 500 slipped 0.5% and broke a five-day winning streak, closing at 6,812.63. The Dow Jones Industrial Average dropped 0.9% to 47,289.33, while the Nasdaq composite dipped 0.4% to 23,275.92.

Last week's rally was largely due to rising hopes that the Federal Reserve will cut its main interest rate next week to help shore up the slowing job market.

Jobs are under pressure at U.S. manufacturers, and the majority in a survey by the Institute for Supply Management said they're still focused more on managing headcount than on hiring. Several manufacturers also said tariffs are continuing to make things complicated.

"Conditions are more trying than during the coronavirus pandemic in terms of supply chain uncertainty," one manufacturer told the ISM.

Yields for longer-term Treasurys rose in the bond market, part of a worldwide climb for yields after Bank of Japan Gov. Kazuo Ueda indicated the central bank may raise its benchmark rate at its meeting later this month.

Japan's benchmark interest rate has remained near zero for years in hopes of reviving sluggish growth. Now inflation is holding above the Bank of Japan's target of about 2%.

"The prospect of the Bank of Japan resuming its hiking cycle a bit sooner than previously thought has sent tremors through global bond and equity markets this week, but we suspect they could nonetheless weather further tightening," Thomas Mathews of Capital Markets said in a commentary.

When bonds are paying higher yields, they can attract investors who would otherwise buy stocks or cryptocurrencies. Higher yields undercut prices for all kinds of investments, particularly those seen as the most expensive.

Bitcoin, which was soaring around $125,000 in October, dropped toward $85,500. That's down roughly 6% from a day earlier. It was trading around $86,650 early Tuesday.

Crypto industry stocks fell, with Coinbase Global down 4.8% and Robinhood Markets losing 4.1%.

On the winning side of Wall Street was Synposys, which rose 4.9%. It said Nvidia is investing $2 billion in its stock as part of an expanded partnership. Nvidia, which has become Wall Street's most influential stock, swung from an early loss to a gain of 1.6%.

The markets had a mixed reaction to what seems like a strong start for the holiday shopping season. Consumer spending during the Black Friday and Cyber Monday retailing bonanza was expected to exceed expectations, despite uncertainty over the outlook for the U.S. economy.

Williams-Sonoma climbed 1.3%, but Best Buy fell 2.6%.

In Europe, France's CAC 40 slipped 0.3% on Monday, dragged down in part by a 5.8% loss for Airbus.

The European aerospace giant said Monday that most of its fleet of 6,000 A320 passenger jets have received an update after a weekend software glitch that could have affected flight controls. Travelers faced minor disruptions as airlines scrambled to push the software updates out after Airbus warned of the problem Friday.

In other dealings early Tuesday, U.S. benchmark crude oil gained 2 cents to $59.34 per barrel. Brent crude, the international standard, shed 4 cents to $63.13 pert barrel.

The dollar rose to 155.61 Japanese yen from 155.41 yen. The euro climbed to $1.1612 from $1.1608.

____

AP Business Writer Stan Choe contributed.

Continue Reading...

Popular

Resilient in face of Trump tariffs, world economy is forecast to grow 3.2% this year, OECD says

WASHINGTON (AP) — The world economy has proven surprisingly durable in the face of President Donald Trump’s trade wars, the Organization for Economic Cooperation and Development said Tuesday, upgrading its outlook for global and U.S. economic growth this year.

OpenAI Takes Equity Stake In Thrive Holdings, AI Giant Will Embed Teams In Joshua Kushner-Led Company To 'Boost' Speed And Accuracy

OpenAI is expanding its enterprise reach by taking a stake in Thrive Holdings to embed AI teams in traditional service firms, while also exploring ad-based revenue in ChatGPT, considering a $6 billion share sale that could lift its valuation to $500 billion, and generating far more revenue than the widely reported $13 billion.

Copper Is Tight, Silver Is Rising - And This Early Nevada Play Hits the Timing Perfectly - Ad

AI, electrification, battery storage, and data centers are pushing copper and silver demand sharply higher, even as supply stays tight. This region in Nevada offers rare multi-metal potential, and a new company has secured land in a district the surging district. It's one of the cleanest timing setups in the sector right now.

AI may be scoring your college essay. Welcome to the new era of admissions

Students applying to college know they can’t — or at least shouldn’t — use AI chatbots to and personal statements. So it might come as a surprise that some schools are now using artificial intelligence to read them.

Cathie Wood Doubles Down On Bitcoin ETF Amid Crypto Chaos, Drops $3.9M On This Amazon Rival

On Monday, Cathie Wood‘s Ark Invest executed significant trades, including notable purchases of ARK 21Shares Bitcoin ETF (BATS:ARKB), 

Investing Legend Hints the End May Be Near for These 3 Iconic Stocks - Ad

Futurist Eric Fry say Amazon, Tesla and Nvidia are all on the verge of major disruption. To help protect anyone with money invested in them, he's sharing three exciting stocks to replace them with. He gives away the names and tickers completely free in his brand-new "Sell This, Buy That" broadcast.

16 Stocks To Buy If You Want To Escape The AI Hype

Bank of America is pointing investors toward 16 overlooked stocks with strong fundamentals and no direct ties to the AI boom—offering a safer path beyond the hype.

Indigenous groups get the spotlight at UN climate talks, but some say visibility isn't power

BELEM, Brazil (AP) — Indigenous people are used to adapting, so when the power failed at their kickoff event at this year's , they rolled with it. Participants from around the world sweated through song, dance and prayers, improvising without microphones and cooling themselves with fans made of paper or leaves.

Trump Signs Law to Launch Dollar 2.0 - Ad

Trump just signed law S.1582, unleashing the biggest money shift in 100+ years. For the first time since 1913, private firms - not the Fed - can mint a "Dollar 2.0." Treasury says it could drain $6.6T from banks and pay 10X current savings rates. Early investors in minting firms could see 40X returns by 2032.

Trump attacks ABC News correspondent Mary Bruce in angry response to three sharp questions

NEW YORK (AP) — President Donald Trump denounced ABC News' Mary Bruce as a “terrible reporter” Tuesday and threatened the network's license to broadcast after she asked him three sharp questions at the White House.

The Next Biggest Bull Run In Over 50 Years - Ad

Gold has hit all-time highs, breaking $4,000 an ounce - but history shows it could be on the verge of its biggest bull run in over half a century... triggered by a likely major event, eerily similar to what happened in the 1970s. (It's NOT inflation or anything you're likely expecting.) Now, a top analyst says you can capture ALL of the upside without touching a risky miner or a boring exchange-traded fund. He sees extraordinary potential gains long term with very little risk.

Trump Withdraws Support For 'Wacky' Marjorie Taylor Greene In Sudden, Fiery Split: 'I Can't Take...'

President Donald Trump said he is withdrawing his endorsement of longtime ally Rep. Marjorie Taylor Greene — here's what happened.

The $43B Big Pharma Story is Starting Over-With a New Player - Ad

Big Pharma once paid $43B for a small biotech with a similar platform. Now, a new company is following that same playbook, leveraging its patented delivery technology to attract partnerships and near-term revenue potential.

Silver Soars To Record Highs: It's Up 95% In 2025, The Best Year Since 1979

Silver prices surge over 5% as investors rush to secure metal amid tight supplies and global shortage concerns, driving up stocks and mining equities.

Iran confirms seizure of oil tanker in the Strait of Hormuz

TEHRAN, Iran (AP) — Iran on Saturday confirmed as it traveled through the narrow Strait of Hormuz over violations including carrying an illegal consignment, state media reported.

Weiss Gold Veteran Makes Shocking New Call - Ad

Weiss expert Sean Brodrick went out on a limb last year and declared a historic event would send the yellow metal to $3,150. People laughed at him at the time, but he was off by just two days. Now, Sean has a shocking new prediction for gold ... and reveals a little-known way to get ahead of this bull market.

AT&T reached a $177M data breach settlement. What consumers should know about claiming their money

NEW YORK (AP) — AT&T has reached a combined $177 million settlement over two . And impacted consumers have a little over a month left to file a claim for their chunk of the money.

Zohran Mamdani Says No More Thanking Veterans Today, Forgetting Tomorrow — Trump, Obama And Others Express Gratitude For Service

America's top political and tech leaders — including Donald Trump, Barack Obama, Tim Cook, and Sundar Pichai — marked Veterans Day 2025 with tributes honoring the courage and sacrifice of U.S. service members.

The Smart Money Copper Trade - Ad

Only one lines up grade, scale potential, and Quebec power like this. Insider alignment is real. Stepouts are opening new zones. With EVs and grid buildouts rising, this could be the timely copper idea you have been waiting for.

Nvidia, Dell, Coinbase, Gorilla Technology And Archer Aviation: Why These 5 Stocks Are On Investors' Radars Today

U.S. stocks closed lower on Monday, with the Dow slipping 1.2% to 46,590.24, the S&P 500 easing 0.92% to 6,672.41, and the Nasdaq dipping 0.84% to 22,708.07. These are the top stocks that gained the attention of retail traders and investors through the day:

Donald Trump Administration's Unprecedented Investment In Private Firms Raises Eyebrows

President Trump administration has invested over $10 billion of taxpayer funds in private companies deemed crucial to national security.

Legally "Skim" $6,361 Into Your Account? - Ad

A former hedge fund manager is now sharing his "Skim Codes" with regular people. They're not stocks. They're not crypto. They're 18-character codes designed to profit from recent market conditions. All you have to do is punch them into an ordinary brokerage account. 84% of these codes have given people the chance to generate cash payouts so far... and his next code is going out any day now.

All 14 victims identified from fiery UPS cargo plane crash in Louisville

LOUISVILLE, Ky. (AP) — A grandfather and his young granddaughter. An electrician with two young children. A woman standing in line at a scrap metal business.

Serbian protesters vow to prevent real estate project linked to Trump son-in-law Kushner

BELGRADE, Serbia (AP) — Thousands of protesters in Serbia symbolically formed a human shield Tuesday around a bombed-out military complex, vowing to protect it from redevelopment as a luxury compound by a company linked to U.S. President Donald Trump’s son-in-law .

Inside: What's Going on Behind the Scenes in DC? - Ad

Former CIA officer Buck Sexton just met with Trump and VP J.D. Vance - and what he uncovered inside the West Wing is stunning. With ties to Tulsi Gabbard, Mike Johnson, Kash Patel, and more, he's rushing this urgent interview to reveal shocking secrets unfolding behind the scenes right now.

Warren Buffett Initiates Alphabet Position, Trims Apple In Q3 — Here Are Berkshire's Moves

Warren Buffett's Berkshire Hathaway took a new stake in a member of the Magnificent Seven, while lowering its stake in Apple in the third quarter.

Trump Hints At Tax Cut, John Bolton Warns Of Peace Prize Ambitions And More: This Week in Politics

Trump hints at major income tax cuts, while political tensions rise over military orders, Russia policy, and government shutdown threats.

$270,000 Drug. One Competitor. Billion-Dollar Market. - Ad

Phase 3 trial targets recurrent pericarditis with an oral therapy that could disrupt the only approved treatment. And their heart failure program launches in 2026.

Preliminary findings show a fatigue crack caused a Keystone Pipeline oil spill in North Dakota

BISMARCK, N.D. (AP) — A fatigue crack in the led to an that released thousands of barrels of oil onto farmland, according to the pipeline operator.

DOJ Greenlights Strikes on Drug Boats, Citing Fentanyl as Potential Chemical Weapon

The DOJ has classified Fentanyl as a potential chemical weapon. This classification has led to the authorization of strikes on drug-smuggling boats.

Copper Is Tight, Silver Is Rising - And This Early Nevada Play Hits the Timing Perfectly - Ad

AI, electrification, battery storage, and data centers are pushing copper and silver demand sharply higher, even as supply stays tight. This region in Nevada offers rare multi-metal potential, and a new company has secured land in a district the surging district. It's one of the cleanest timing setups in the sector right now.

Why 12-Year-Old Mark Zuckerberg Built A Little Messaging Network For The Family Member Who Reportedly Wrote Him $100,000 Check To Start Facebook

Preteen Mark Zuckerberg's early coding projects, including the family messaging system ZuckNet, combined with strong family support and a reported $100,000 check from his father, foreshadowed his creation of Facebook and Meta's later rise to a $1.54 trillion company.

Investing Legend Hints the End May Be Near for These 3 Iconic Stocks - Ad

Futurist Eric Fry say Amazon, Tesla and Nvidia are all on the verge of major disruption. To help protect anyone with money invested in them, he's sharing three exciting stocks to replace them with. He gives away the names and tickers completely free in his brand-new "Sell This, Buy That" broadcast.

Everything Funnels Into Nvidia's Earnings

Nvidia is the main event today, but Walmart and the September jobs report will shape the rest of the week.

Trump Signs Law to Launch Dollar 2.0 - Ad

Trump just signed law S.1582, unleashing the biggest money shift in 100+ years. For the first time since 1913, private firms - not the Fed - can mint a "Dollar 2.0." Treasury says it could drain $6.6T from banks and pay 10X current savings rates. Early investors in minting firms could see 40X returns by 2032.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright systemtrading.ca
Privacy Policy | Terms of Service